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Information about Symmetrel

Amantadine is an antiviral agent used for treatment and prevention certain types of flu. It may also be administered to treat Parkinson disease and uncontrolled muscle movements caused by some drugs. The exact mechanism of Amantadine action is unknown.

It may also be used for other conditions as determined by your doctor.

You should not use Amantadine in case you have any condition mentioned below: you are allergic to any ingredient in Amantadine; you have uncontrolled narrow-angle glaucoma.

In such cases it is obligatory to consult with your doctor or health care provider before taking this drug.

Before using Amantadine

Before using Amantadine you should tell your doctor if you have any medical conditions listed below: you are pregnant, planning to become pregnant, or are breast-feeding a baby; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you have allergies to medicines, foods, or other substances; you have a history of heart problems (eg, congestive heart failure), swelling of your hands or feet, mental or mood problems, suicidal thoughts or actions, seizures, glaucoma, low blood pressure, dizziness when you stand or sit up, an eczema-like rash, or kidney or liver problems.

Be aware that Amantadine may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: thioridazine because tremors may be worsened in Parkinson patients; anticholinergics (eg, scopolamine), hydrochlorothiazide, quinidine, quinine, stimulants (eg, caffeine, methylphenidate, pseudoephedrine), or triamterene because they may increase the risk of Amantadine 's side effects.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Amantadine

Take this medicine as recommended by your physician. Amantadine should be taken orally with or without food.

Take Amantadine for the full course of treatment. Do not stop using Amantadine even if you feel better in a few days. It helps to eliminate your infection completely.

In case you miss a dose of Amantadine, take it as soon as possible. If it is almost time for your next intake, skip the missed dose and take it according to your regular dosing schedule. Do not take double doses to catch up.

Important safety information

Be careful when driving, operating machinery, or performing other hazardous activities as Amantadine usage may lead to drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Try to avoid such activities.

Dizziness, lightheadedness, or fainting may be increased by alcohol, hot weather, exercise, or fever. For the purpose of prevention them, you should sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.

Be careful that heatstroke may occur in case you become overheated in hot weather or while you are being active.

Amantadine is effective against certain types of the flu. It does work against other viral infections (the common cold).

Use Amantadine for the full course of treatment, as any failures may decrease the effectiveness of Amantadine and may increase the risk that the bacteria will no longer be sensitive to Amantadine and will not be able to be treated by this or certain other antibiotics in the future.

In case you are using Amantadine to treat Parkinson disease, you should increase physical activity slowly as your symptoms improve.

Do not suddenly stop taking Amantadine without first checking with your doctor. Your dose may need to be lowered slowly to avoid side effects. In case you give up taking Amantadine suddenly, you may experience withdrawal symptoms (agitation, hallucinations, paranoia, anxiety, depression, confusion, or slurred speech).

Amantadine may cause Neuroleptic malignant syndrome (NMS). It is a possibly fatal syndrome. Symptoms of NMS are fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; and sweating. Consult with your doctor at immediately in case you have any of these symptoms.

In case your symptoms do not get better or if they get worse, consult with your doctor.

The ELDERLY may be more sensitive to effects of Amantadine. Use it with caution in this group.

Use Amantadine with extreme caution in CHILDREN younger than 1 year old, as safety and effectiveness in this group have not been proved.

PREGNANCY and BREAST-FEEDING

In case you become pregnant, consult with your doctor and discuss the benefits and risks of using this medicine while pregnancy. It is known that Amantadine passes into breast milk. Avoid breast-feeding a baby while using Amantadine.

Possible side effects of Amantadine

You should consult with your doctor in case you have any of side effects especially bothersome listed below: appetite loss; blurred vision; constipation; diarrhea; dizziness; drowsiness; dry mouth or nose; headache; lightheadedness; nausea; strange dreams; tiredness; trouble sleeping.

Seek emergency immediately in case you have any of these severe side effects: severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); agitation; aggression; confusion; depression; fainting; fast or irregular heartbeat; fever; hallucinations; memory loss; mental or mood changes; muscle problems (eg, spasms, uncontrolled movements); paranoid thoughts; personality changes; seizures; severe or persistent drowsiness or trouble sleeping; shortness of breath; swelling of hands, legs, feet, or ankles; thoughts of suicide; trouble urinating; unusual anxiety or irritability; vision changes.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.