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Information about Paxil

Paroxetine is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, obsessive-compulsive disorder (OCD), generalized and social anxiety disorders, posttraumatic stress disorder, and panic disorders with or without the fear of being in open or public places. Paroxetine increases the activity of a chemical in the brain called serotonin. In that way it helps to elevate mood.

It may also be administered for other conditions as determined by your physician.

You should not use Paroxetine in the following cases: you are allergic to any ingredient in it; you are currently taking a phenothiazine (eg, thioridazine) or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days.

In such cases it is obligatory to consult with your doctor or health care provider before taking this drug.

Before using Paroxetine

Before using Paroxetine you should tell your doctor if you have any medical conditions listed below: you are pregnant, planning to become pregnant, or are breast-feeding a baby; you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement; you have allergies to medicines, foods, or other substances; you have a history of seizures or mania, have thoughts of suicide, or have attempted suicide; you have severe liver or kidney disease, an illness that alters your metabolism or blood circulation response, or have had gastrointestinal bleeding; you have a history of narrow-angle glaucoma.

Be aware that Paroxetine may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: cyproheptadine, risperidone, or sumatriptan because the effectiveness of Paroxetine may be decreased; anorexiants (eg, phentermine), dextromethorphan, fenfluramine and its derivatives, l-tryptophan, MAO inhibitors (eg, phenelzine), selegiline, St. John's wort, tramadol, beta-blockers (eg, metoprolol), buspirone, butyrophenones (eg, haloperidol), cimetidine, clonazepam, linezolid, lithium, metoclopramide, nefazodone, sibutramine, sumatriptan, trazodone, or zolpidem because side effects such as serotonin syndrome and central nervous system toxicity may occur; astemizole, dextromethorphan, phenothiazines (eg, thioridazine), St. John's wort, terfenadine, tramadol, anticholinergics (eg, oxybutynin, scopolamine), anticoagulants (eg, warfarin), aripiprazole, beta-blockers (eg, metoprolol), butyrophenones (eg, haloperidol), clozapine, galantamine, H1 antagonists (eg, diphenhydramine), molindone, norepinephrine reuptake inhibitors (eg, atomoxetine), nonsteroidal anti-inflammatory agents (NSAIDs) (eg, ibuprofen), pimozide, propafenone, risperidone, selegiline, trazodone, or tricyclic antidepressants (eg, amitriptyline) because side effects associated with these medicines may be increased by Paroxetine; atypical antipsychotics (eg, risperidone), because the risk of thromboembolic events (clots) may be increased; barbiturate anesthetics (eg, thiopental) used for anesthesia during electroconvulsive therapy (ECT) because the risk of spontaneous seizure is increased.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Paroxetine

Use this medicine as recommended by your physician. Paroxetine should be taken with or without food. It is recommended to take Paroxetine in the morning.

You should know that improvement in your depression may start in several weeks (1-4 weeks). Do not stop taking Paroxetine even if you feel better.

In case you miss a dose of Paroxetine and you are taking it in the morning, take it during the afternoon if you remember. In case you do not remember until the next morning, skip the missed dose and go back to your regular schedule. In case you miss a dose and you are taking one dose daily at bedtime and do not remember until the next day, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. In case you miss more than one dose, consult with your doctor or pharmacist.

Important safety information

Be careful when driving, operating machinery, or performing other hazardous activities as Paroxetine usage may lead to drowsiness, dizziness, blurred vision, or lightheadedness. Try to avoid such activities. Alcohol and certain other medicines may increase the risk of unfavorable reactions while taking Paroxetine.

Do not suddenly stop taking Paroxetine, as you may have WITHDRAWAL symptoms, such as irritability, a state of feeling unwell or unhappy, agitation, dizziness, electric shock sensations, anxiety confusion, headache, lack of energy, mood swings, inability to sleep, or mild mania. Your dose should be decreased gradually.

Children and teenagers who take Paroxetine may be at increased risk for suicidal thoughts or actions. Adults may also be affected. The risk may be greater in patients who have had suicidal thoughts or actions in the past. The risk may also be greater in patients who have had bipolar (manic-depressive) illness, or if their family members have had it.

Look after patients who use Paroxetine closely. Contact the doctor immediately in case new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Consult with your doctor immediately in case any signs of suicidal thoughts or actions take place.

Do not drink alcohol while taking Paroxetine.

Lab tests, including liver function, kidney function, and complete blood cell counts, may be performed while you are using Paroxetine. It is important to control your progress or to check for side effects. Follow all doctor and lab appointments strictly.

Do not use Paroxetine in CHILDREN, as safety and effectiveness have not been proved.

You may experience a prolonged or painful erection while using this medicine. In such case, stop using Paroxetine and consult with your doctor.

PREGNANCY and BREAST-FEEDING

Paroxetine is deleterious to the fetus. In case you could become pregnant, consult with your doctor and discuss the benefits and risks of using Paroxetine while pregnancy. It is known that Paroxetine passes into breast milk. In case you are or will be breast-feeding a baby while you are using Paroxetine, consult with your doctor or pharmacist and discuss the risks to your baby.

Possible side effects of Paroxetine

You should consult with your doctor in case you have any of side effects especially bothersome listed below: abnormal dreams; abnormal ejaculation; abnormal skin sensations; agitation; anxiety; back pain; blurred vision; constipation; decreased appetite; decreased sex drive; diarrhea; difficulty concentrating; difficulty reaching climax/orgasm; dizziness; drowsiness; dry mouth; fatigue; female genital disorders; flushing; gas; headache; impotence; inability to sleep; infection (fever, chills, sore throat); inflamed sinuses; light-headedness; muscle pain; muscle twitch; nausea; nervousness; painful period; rash; runny nose; sleepiness; sore throat; stomach pain; sweating; temporary loss of personal reality; urinary frequency; urination disorder; vomiting; weakness; yawning.

Seek emergency immediately in case you have any of these severe side effects: severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); abnormal bleeding; breathing problems; chest pain; extreme mood swings; heart problems; pounding in the chest; prolonged, painful erection; thoughts of hurting yourself; tremors; unusual bleeding or bruising; worsening of mood or mental state; seizures; worsening of depression.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.

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