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Information about Celebrex

Celecoxib is a COX-2 inhibitor NSAID that is used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual pain, or pain. The exact mechanism of Celecoxib action is unknown. Probably, it blocks certain substances in the body that are connected with inflammation. It may also be administered to decrease the number of polyps (growths) in the rectal area.

It may also be used for other conditions as determined by your doctor.

You should not use Celecoxib in case you have any condition mentioned below: you are allergic to any ingredient in Celecoxib; you have had a severe allergic reaction (eg, severe rash, hives, trouble breathing, growths in the nose, dizziness) to aspirin, an NSAID (eg, ibuprofen), or a sulfonamide (eg, sulfamethoxazole); you have recently had or will be having bypass heart surgery; you have severe liver problems; you are in the last 3 months of pregnancy.

In such cases it is obligatory to consult with your doctor or health care provider before taking this drug.

Before using Celecoxib

Before using Celecoxib you should tell your doctor if you have any medical conditions listed below: you are pregnant, planning to become pregnant, or are breast-feeding a baby; you are taking any prescription or nonprescription medicine, herbal product, or dietary supplement; you have allergies to medicines, foods, or other substances; you have a history of kidney or liver disease, diabetes, or stomach or bowel problems (eg, bleeding, perforation, ulcers); you have a history of swelling or fluid buildup, asthma, growths in the nose (nasal polyps), or mouth inflammation; you have high blood pressure, blood disorders, bleeding or clotting; problems, heart problems (eg, heart failure), or blood vessel disease, or you are at risk for any of these diseases; you have poor health, dehydration or low fluid volume, or low blood sodium levels, you drink alcohol, or you have a history of alcohol abuse.

Be aware that Celecoxib may interact with some medicines. Consult with your health care provider in case you are taking any other drugs, especially any of the following: anticoagulants (eg, warfarin), aspirin, corticosteroids (eg, prednisone), heparin, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine) because risk of stomach bleeding may be increased; fluconazole or probenecid because they may increase the risk of Celecoxib 's side effects; cyclosporine, lithium, methotrexate, or quinolones (eg, ciprofloxacin) because the risk of their side effects may be increased by Celecoxib; angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) or diuretics (eg, furosemide, hydrochlorothiazide) because their effectiveness may be decreased by Celecoxib.

It may not be a complete list of all interactions with other drugs. To prevent any complications you should check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Celecoxib

Take Celecoxib as recommended by your doctor. It is better to take this drug orally with food in case of stomach upset. Nevertheless it does not lower the risk of stomach or bowel problems (eg, bleeding, ulcers). Consult with your doctor or pharmacist in case you experience persistent stomach upset.

It is recommended to take Celecoxib with a full glass of water (8 oz/240 mL).

Try not to lie down for 30 minutes after taking Celecoxib.

In case you miss a dose of Celecoxib, take it as soon as possible. If it is almost time for your next intake, skip the missed dose and take it according to your regular dosing schedule. Do not take double doses to catch up.

Important safety information

Celecoxib usage may lead to dizziness or drowsiness. These effects may be worsened by taking alcohol or certain medicines. Prevent driving or performing any other possibly dangerous actions.

Celecoxib usage may lead to serious stomach ulcers or bleeding. These effects may be worsened by using Celecoxib in high doses, for a long period of time, smoking, or drinking alcohol. Using Celecoxib in combination with food will NOT reduce the risk of such effects.

You should know that Celecoxib is an NSAID. Before you start any new medicine, check the label whether it contains an NSAID (eg, ibuprofen). In case it does or you are not sure, consult with your doctor or pharmacist.

You should not take aspirin if you are taking Celecoxib unless your doctor recommends otherwise.

Celecoxib does not reduce FAP-related cancers in FAP patients. Continue your usual care while you use Celecoxib.

Lab tests, including kidney function, complete blood cell counts, and blood pressure, may be performed while you are using Celecoxib. It is important to control your progress or to check for side effects. Follow all doctor and lab appointments strictly.

The ELDERLY are likely to be more sensitive to its effects, especially stomach bleeding and kidney problems. Use Celecoxib with caution in this group.

Use Celecoxib with extreme caution in CHILDREN younger than 18 years old as safety and effectiveness in this group have not been proved.

PREGNANCY and BREAST-FEEDING

Celecoxib may be deleterious to the fetus. You should not use it during the last 3 months of pregnancy. In case you could become pregnant, consult with your doctor and discuss the benefits and risks of using Celecoxib while pregnancy. It is clear that Celecoxib passes into breast milk. Avoid breast-feeding a baby while using Celecoxib.

Possible side effects of Celecoxib

You should consult with your doctor in case you have any of side effects especially bothersome listed below: constipation; diarrhea; dizziness; gas; headache; heartburn; nausea; sore throat; stomach upset; stuffy nose.

Seek emergency immediately in case you have any of these severe side effects: severe allergic reactions (rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody or black, tarry stools; change in the amount of urine produced; chest pain; confusion; dark urine; depression; fainting; fast or irregular heartbeat; fever, chills, or persistent sore throat; hearing loss; mental or mood changes; numbness of an arm or leg; one-sided weakness; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe headache or dizziness; severe or persistent stomach pain or nausea; severe vomiting; shortness of breath; sudden or unexplained weight gain; swelling of hands, legs, or feet; unusual bruising or bleeding; unusual joint or muscle pain; unusual tiredness or weakness; vision or speech changes; vomit that looks like coffee grounds; yellowing of the skin or eyes.

What is the expiration date of the pills?

This information is mentioned on each blister. The expiration date is 2 years from the date of manufacture.